TY  -  JOUR
AU  -  Gans, Alessandro
AU  -  Valcamonica, Gloria
AU  -  Cardillo, Alessandra
AU  -  Gallo Cassarino, Serena
AU  -  Bruzzaniti, Davide
AU  -  Muscia, Francesco
AU  -  Prelle, Alessandro
T1  -  Subacute onset neuropathy and encephalopathy: 
disulfiram poisoning vs Bickerstaff syndrome
PY  -  2024
Y1  -  2024-10-01
DO  -  10.1727/4393.43944
JO  -  Rivista di Neurologia
JA  -  Riv Neurol
VL  -  1
IS  -  4
SP  -  207
EP  -  209
PB  -  Il Pensiero Scientifico Editore
SN  -  3035-3599
Y2  -  2026/07/08
UR  -  http://dx.doi.org/10.1727/4393.43944
N2  -  Summary. We report the clinical case of a former alcoholic treated with disulfiram who presented with acute-onset ataxic sensorimotor demyelinating polyradiculoneuritis, ophthalmoplegia, and altered mental status, with evidence of toxic-metabolic basal ganglia encephalopathy on brain magnetic resonance imaging. After ruling out Bickerstaff syndrome, a diagnosis of drug-induced Wernicke’s encephalopathy was confirmed. Chronic disulfiram use may lead to the development of polyneuropathy and Wernicke’s encephalopathy, requiring immediate discontinuation of therapy and vitamin supplementation.
ER  -